Product Name: Salcaprozate Sodium
Alias: SNAC; Salcaprozate Sodium; Salcaprozate sodium; Salcaprozate Sodium (SNAC); sodium 8-(2-hydroxybenzamido)octanoate; sodium,8-[(2-hydroxybenzoyl)amino]octanoate; SODIUM 8-(2-HYDROXYBENZAMIDO)OCTANOATE (SNAC); SNAC,sodium 8-[(2-hydroxybenzoyl)amino]octanoate; Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt
CAS No.: 203787-91-1
EINECS: 231-019-4
Chemical Formula: C15H20NNaO4
Molecular Weight: 301.31
Brief Introduction:
Sodium 8-(2-hydroxybenzamino)octanoate, which is also called Salcaprozate sodium(SNAC), it is an oral absorption enhancer with potential as a delivery agent for oral forms of heparin, insulin and semaglutide. Salcaprozate sodium increases lipophilicity induced by non-covalent macromolecular complexation, thereby increasing passive transcellular penetration of intestinal epithelial cells.
SNAC is also an absorption enhancer for dicarbonate phosphate compounds, which is used for treating gastrointestinal diseases, especially for gastrointestinal diseases caused by malabsorption of dicarbonate phosphate.
| Test Items |
Specifications |
Test Methods |
| Appearance |
White or off-white solid |
Visual |
| Identification |
Meets the requirements |
H-NMR |
| Purity |
Not less than 90.0% |
HPLC |
| Impurity A |
Not more than 0.15% |
HPLC |
| Impurity E |
Not more than 0.15% |
HPLC |
| Impurity G |
Not more than 0.5% |
HPLC |
| The maximum unknown single impurity |
Not more than 1.0% |
HPLC |
| Total impurities |
Not more than 10.0% |
HPLC |
| Isopropyl alcohol |
Not more than 5000ppm |
GC |
| Methyl alcohol |
Not more than 5000ppm |
GC |
| Ethanol |
Not more than 5000ppm |
GC |
| DMF |
Not more than 880ppm |
GC |
| Benzene |
Not more than 2ppm |
GC |
Storage Conditions:
Kept at 2℃~8℃ under an inert atmosphere.
For reducing the absorption of the moisture, it should be slowly warmed to ambient temperature before opened.
Shelf Life: 24 months.
