Product Description

Product Name: Salcaprozate Sodium

Alias: SNAC; Salcaprozate Sodium; Salcaprozate sodium; Salcaprozate Sodium (SNAC); sodium 8-(2-hydroxybenzamido)octanoate; sodium,8-[(2-hydroxybenzoyl)amino]octanoate; SODIUM 8-(2-HYDROXYBENZAMIDO)OCTANOATE (SNAC); SNAC,sodium 8-[(2-hydroxybenzoyl)amino]octanoate; Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt

CAS No.: 203787-91-1

EINECS: 231-019-4

Chemical Formula: C15H20NNaO4

Molecular Weight: 301.31

 

Brief Introduction:

Sodium 8-(2-hydroxybenzamino)octanoate, which is also called Salcaprozate sodium(SNAC), it is an oral absorption enhancer with potential as a delivery agent for oral forms of heparin, insulin and semaglutide. Salcaprozate sodium increases lipophilicity induced by non-covalent macromolecular complexation, thereby increasing passive transcellular penetration of intestinal epithelial cells.

SNAC is also an absorption enhancer for dicarbonate phosphate compounds, which is used for treating gastrointestinal diseases, especially for gastrointestinal diseases caused by malabsorption of dicarbonate phosphate.

 

Test Items	Specifications	Test Methods
Appearance	White or off-white solid	Visual
Identification	Meets the requirements	H-NMR
Purity	Not less than 90.0%	HPLC
Impurity A	Not more than 0.15%	HPLC
Impurity E	Not more than 0.15%	HPLC
Impurity G	Not more than 0.5%	HPLC
The maximum unknown single impurity	Not more than 1.0%	HPLC
Total impurities	Not more than 10.0%	HPLC
Isopropyl alcohol	Not more than 5000ppm	GC
Methyl alcohol	Not more than 5000ppm	GC
Ethanol	Not more than 5000ppm	GC
DMF	Not more than 880ppm	GC
Benzene	Not more than 2ppm	GC

 

Storage Conditions:
Kept at 2℃~8℃ under an inert atmosphere.
For reducing the absorption of the moisture, it should be slowly warmed to ambient temperature before opened.

 

Shelf Life: 24 months.

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